ENTERIC FEVER,DIABETES MELLITUS SINCE 9 YEARS, HYPERTENSION SINCE 1 WEEK WITH ANEMIA-MCHC SECONDARY TO NUTRITIONAL CAUSE


A 49 years old female who is a house wife by occupation came with C/O

FEVER SINCE 2 WEEKS


HOPI

Patient was apparently asymptomatic 9 years back then she started having bleeding per vagina for which she went to hospital & Diagnosed to have ? Fibroid uterus for which she went to a private hospital in hyderabad for hysterectomy as advised in local hospital. Then she had high sugars for the first time (Around 450mg/dl).So she was admitted in the hospital & hysterectomy was done after controlling the sugars with Insulin.

Then she was discharged with the following advice 

Tab.GLIME M1 PO BD & continued the tablet for 3 years

Along with diabetic diet. 

Then she came to our OP for Follow then she was prescribed with Tab.GLIME M2 PO BD which she used for 2 years. Then she came to our OP for Follow up then she was escalated to Tab.GLIME M3 PO BD.


March 2023 [1ST VISIT]


She had ulcer over left great toe for which she was admitted in our hospital & got relieved.


18th of November 2023 [ 2ND VISIT]

SHE HAD DEVELOPED SWELLING IN THE RIGHT FOOT EXTENDING UPTO MIDDLE OF THE LEG WHICH WAS INSIDIOUS IN ONSET,GRADUALLY PROGRESSIVE ,NO AGGREVATING AND RELIVING FACTORS.SWELLING WAS ASSOCIATED WITH PAIN , WHICH WAS DRAGGING TYPE , NON RADIATING , INTERMITTENT , AGGRAVATED ON WALKING , NO RELIEVING FACTORS .

H/O FEVER WAS PRESENT ON AND OFF RELIEVED ON TAKING MEDICATION

NO H/O TRAUMATIZED 

SHE THEN CAME TO THIS HOSPITAL ON 16-11-2023 and WAS DIAGNOSED WITH CELLULITIS OF RIGHT LEG

THEN, PATIENT WAS ADMITTED, EVALUATED,AND WAS TREATED FOR 7 DAYS.


PAST HISTORY

K/C/O DIABETES MELLITUS SINCE 10 YEARS ON INJ HUMAN MIXTARD 30U-25U

NOT A K/C/O ASTHMA,COPD,HYPERTENSION,EPILEPSY,TUBERCULOSIS

H/O HYSTERECTOMY 30 YEARS AGO


GENERAL PHYSICAL EXAMINATION -

PT IS CONSCIOUS,COHERENT AND COOPERATIVE

No pallor 

No icterus 

No cyanosis 

No clubbing 

No lymphadenopathy 

Pitting type of pedal edema is 

present.


TEMP - AFEBRILE

BP - 130/70 MM OF HG

PR - 98BPM ,RR - 16 CPM

SPO2 - 99% @RA

CVS- S1,S2 HEARD , RS - B/L AE +

LOCAL EXAMINATION

INSPECTION :

SWELLING OF RIGHT LEG PREENT EXTENDING UPTO MIDDLE 1/3RD OF RT LEG

REDNESS PRESENT

NO SCARS,SINUSES,ENGORGED VEINS,VISIBLE PULSATIONS.

PALPATION

ALL INSPECTORY SIGNS ARE CONFIRMED

LOCAL RISE OF TEMPERATURE PRESENT

TENDERNESS PRESENT

PITTING TYPEOF EDEMA PRESENT EXTENDING UPTO MIDDLE 1/3RD OF THE LEG

PERIPHERAL PULSES PALPABLE


INVESTIGATIONS 

POST LUNCH BLOOD SUGAR 16-11-2023 110 mg/dl

SERUM CREATININE 16-11-2023 0.9

COMPLETE URINE EXAMINATION (CUE) 16-11-2023

COLOUR Pale yellow

APPEARANCE Clear

REACTION Acidic

SP.GRAVITY 1.010

ALBUMIN ++

SUGAR +++

BILE SALTS Nil

BILE PIGMENTS Nil

PUS CELLS 3-6

EPITHELIAL CELLS 2-4

RED BLOOD CELLS Nil

CRYSTALS Nil

CASTS Nil

AMORPHOUS DEPOSITS Absent

OTHERS Nil

ABG 16-11-2023

PH 7.47

PCO2 28.4

PO2 82.9

HCO3 20.5

St.HCO3 22.8

BEB -1.9

BEecf -2.6

TCO2 42.2

O2 Sat 96.9

O2 Count 13.6

COMPLETE URINE EXAMINATION (CUE) 16-11-2023

COLOUR Pale yellow

APPEARANCE Clear

REACTION Acidic

SP.GRAVITY 1.010

ALBUMIN Nil

SUGAR ++++

BILE SALTS Nil

BILE PIGMENTS Nil

PUS CELLS 3-4

EPITHELIAL CELLS 2-4

RED BLOOD CELLS Nil

CRYSTALS Nil

CASTS Nil

AMORPHOUS DEPOSITS Absent

OTHERS Nil

COMPLETE BLOOD PICTURE (CBP) 16-11-2023 10:33:PM

HAEMOGLOBIN 9.0 gm/dl 15.0-12.0 gm/dl

TOTAL COUNT 10800 cells/cumm 10000-4000 cells/cumm

NEUTROPHILS 62 % 80-40 %

LYMPHOCYTES 32 % 40-20 %

EOSINOPHILS 00 % 6-1 %

MONOCYTES 06 % 10-2 %

BASOPHILS 00 % 2-0 %

PLATELET COUNT 3.87

SMEAR microcytic hypochromic anemia

HBsAg-RAPID 16-11-2023 Negative

LIVER FUNCTION TEST (LFT) 16-11-2023

Total Bilurubin 0.51 mg/dl 1-0 mg/dl

Direct Bilurubin 0.20 mg/dl 0.2-0.0 mg/dl

SGOT(AST) 14 IU/L 31-0 IU/L

SGPT(ALT) 19 IU/L 34-0 IU/L

ALKALINE PHOSPHATE 143 IU/L 98-42 IU/L

TOTAL PROTEINS 6.4 gm/dl 8.3-6.4 gm/dl

ALBUMIN 3.91 gm/dl 5.2-3.5 gm/dl

A/G RATIO 1.57

RFT 16-11-2023 10:33:PM

UREA 18 mg/dl

CREATININE 0.7 mg/dl

URIC ACID 5.7 mg/dl

CALCIUM 10.1 mg/dl

PHOSPHOROUS 3.3 mg/dl

SODIUM 135 mEq/L

POTASSIUM 3.7 mEq/L

CHLORIDE 101 mEq/L 98-107 mEq/L

POST LUNCH BLOOD SUGAR 17-11-2023 393 mg/dl

RFT 19-11-2023

UREA 18 mg/dl

CREATININE 0.6 mg/dl

URIC ACID 2.6 mg/dl

CALCIUM 10.1 mg/dl

PHOSPHOROUS 3.4 mg/dl

SODIUM 137 mEq/L

POTASSIUM 4.2 mEq/L

CHLORIDE 102 mEq/L

COMPLETE BLOOD PICTURE (CBP) 20-11-2023

HAEMOGLOBIN 8.9 gm/dl

TOTAL COUNT 12200 cells/cumm

NEUTROPHILS 68 %

LYMPHOCYTES 26 %

EOSINOPHILS 00 %

MONOCYTES 06 %

BASOPHILS 00 % 2-0 %

PLATELET COUNT 4.33

SMEAR Microcytic hypochromic anemia with leukocytosis


FINAL DIAGNOSIS 

CELLULITIS OF RIGHT LEG


Treatment Given

DIABETIC DIET

INJ AUGMENTIN 1.2 G IV BD

TAB PAN 40MG PO OD BBF

TAB CHYMORAL FORTE PO TID

INJ METROGYL 500MG IV TID

TAB ULTACET PO BD

TAB MVT PO OD

TAB VITAMIN C PO OD

ADEQUATE GLUCOSE CONTROL

RIGHT LOWER LIMB ELEVATION

REGULAR MAGNESIUM SULPHATE AND GLYCERINE DRESSINGS


DATE OF DISCHARGE : 23/11/2023

THEN THE PATIENT WAS DISCHARGED ON 23/11/2023 WITH THE FOLLOWING ADVICE : 

DIABETIC DIET

TAB.GLIMI M1 PO OD BBF

TAB.MVT PO OD FOR 1 WEEK 

TAB.VITAMIN C PO OD FOR 1 WEEK 

LIMB ELEVATION.


[5/1, 9:20 AM] Rakesh Biswas Sir GM HOD: @⁨Narsimha Reddy sir Pg Gm⁩ You can see in meticulous detail how maximal dose of sulfonylurea titration actually brought her glucose values to ideal levels before the intern who was caring for her regularly and following her up abruptly left and she again slipped into hyperglycemia and sepsis with which we are still struggling in the last two admissions over last one month!

[5/1, 9:51 AM] Narsimha Reddy sir Pg Gm: Yes Sir there was a good control

With gradual  uptitration of GLIMEPERIDE over those 22 days Span. Really appreciate the effort of the intern 👏. It was also clearly evident how a good diet can add up the Control.

[5/1, 9:52 AM] Narsimha Reddy Pg Gm: Hoping to switch back to OHAs

[5/1, 10:01 AM] Rakesh Biswas Sir GM HOD: Let's not attempt it again before we are sure of the PaJR care she's going to receive

[5/1, 11:56 AM] +91 hemant c sir: We shall take regular updates on their activities like food and medication to better understand the glucose control



18th OF APRIL , 2024 [ 3rd VISIT TO THIS HOSPITAL]

SHE HAD COMPLAINTS OF FEVER SINCE 13 DAYS A/W CHILLS ,MORE AT MORNING, RELIEVED WITH MEDICATION A/W PROFUSE SWEATING.

H/O INCREASED FREQUENCY OF LOOSE STOOLS ON AND OFF SINCE 2 MONTHS 

NO H/O BURNING MICTURITION 

NO H/O PAIN ABDOMEN , VOMITINGS

NO H/O CHEST PAIN, PALPITATIONS 

NO H/O COLD,COUGH

NO H/O PEDAL EDEMA, DRUG NON-COMPLIANCE


HISTORY OF PAST ILLNESS :

K/C/O DM SINCE 8 YEARS ON

GLIMIPERIDE

N/K/C/O HTN ; THYROID DISORDERS , ASTHMA , TB , EPILEPSY , CAD , CVA


MENSTRUAL HISTORY :

HYSTERECTOMY DONE 9 YEARS AGO


Chest Xray on 18/04/24



USG Abdomen on 18/04/24 :



Insulin drip chart - 18/4/24



Morning VBG - 19/4/24





HBsAg-RAPID 18-04-2024 12:32:PM

Negative


  COMPLETE URINE EXAMINATION (CUE) 18-04-2024 12:32:PM

 COLOUR Pale yellow

 APPEARANCE Clear

 REACTION Acidic

 SP.GRAVITY 1.010

 ALBUMIN Nil

 SUGAR Nil

 BILE SALTS Nil

 BILE PIGMENTS Nil

 PUS CELLS 3-4

 EPITHELIAL CELLS 2-3

 RED BLOOD CELLS Nil

 CRYSTALS Nil

 CASTS Nil

 AMORPHOUS DEPOSITS Absent

 OTHERS Nil


 LIVER FUNCTION TEST (LFT) 18-04-2024 12:34:PM

 Total Bilurubin 1.46 mg/dl 1-0 mg/dl

 Direct Bilurubin 0.43 mg/dl 0.2-0.0 mg/dl

 SGOT(AST) 10 IU/L 31-0 IU/L

 SGPT(ALT) 10 IU/L 34-0 IU/L

 ALKALINE PHOSPHATASE 232 IU/L 98-42 IU/L

 TOTAL PROTEINS 7.0 gm/dl 8.3-6.4 gm/dl

 ALBUMIN 3.67 gm/dl 5.2-3.5 gm/dl

 A/G RATIO 1.10


  RFT 18-04-2024 12:34:PM

 UREA 37 mg/dl 42-12 mg/dl

 CREATININE 1.3 mg/dl 1.1-0.6 mg/dl

 URIC ACID 4.1 mmol/L 6-2.6 mmol/L

 CALCIUM 9.6 mg/dl 10.2-8.6 mg/dl

 PHOSPHOROUS 3.6 mg/dl 4.5-2.5 mg/dl

 SODIUM 136 mmol/L 145-136 mmol/L

 POTASSIUM 4.6 mmol/L. 5.1-3.5 mmol/L.

 CHLORIDE 98 mmol/L 98-107 mmol/L


POST LUNCH BLOOD SUGAR 18-04-2024 12:35:PM 493 mg/dl 140-0 mg/dl

 PERIPHERAL SMEAR 18-04-2024 12:55:PM RBC : Microcytic hypochromic WBC :increased counts on smear PLATELET : Adequate


 ABG 18-04-2024 03:42:PM

 PH 7.41

 PCO2 24.0

 PO2 90.8

 HCO3 15.2

 St.HCO3 18.0

 BEB -7.9

 BEecf -8.4

 TCO2 32.2

 O2 Sat 96.6

 O2 Count 11.8

  ABG 18-04-2024 10:54:PM

 PH 7.36

 PCO2 31.7

 PO2 39.7

 HCO3 17.5

 St.HCO3 18.6

 BEB -6.8

 BEecf -6.9

 TCO2 38.1

 O2 Sat 75.4

 O2 Count 7.7


 SERUM ELECTROLYTES (Na, K, C l) 18-04-2024 10:54:PM

 SODIUM 128 mmol/L 145-136 mmol/L

 POTASSIUM 3.8 mmol/L 5.1-3.5 mmol/L

 CHLORIDE 104 mmol/L 98-107 mmol/L


  SERUM ELECTROLYTES (Na, K, C l) 19-04-2024 11:54:AM

 SODIUM 134 mmol/L 145-136 mmol/L

 POTASSIUM 3.9 mmol/L 5.1-3.5 mmol/L

 CHLORIDE 105 mmol/L 98-107 mmol/L


 COMPLETE URINE EXAMINATION (CUE) 19-04-2024 11:54:AM

 COLOUR Pale yellow

 APPEARANCE Clear

 REACTION Acidic

 SP.GRAVITY 1.010

 ALBUMIN +

 SUGAR Nil

 BILE SALTS Nil

 BILE PIGMENTS Nil

 PUS CELLS 2-4

 EPITHELIAL CELLS 2-3

 RED BLOOD CELLS Nil

 CRYSTALS Nil

 CASTS Nil

 AMORPHOUS DEPOSITS Absent

 OTHERS Nil


  ABG 19-04-2024 04:44:PM

 PH 7.42

 PCO2 28.7

 PO2 73.8

 HCO3 18.5

 St.HCO3 20.5

 BEB -4.7

 BEecf -5.1

 TCO2 39.1

 O2 Sat 95.7

 O2 Count 11.4


 SERUM ELECTROLYTES (Na, K, C l) 19-04-2024 11:06:PM

 SODIUM 137 mmol/L 145-136 mmol/L

 POTASSIUM 4.0 mmol/L 5.1-3.5 mmol/L

 CHLORIDE 105 mmol/L 98-107 mmol/L


HEMOGRAM 19/4/24

HB - 7.6

TLC-14,400

PCV - 22.8

RBC - 3.9

SMEAR - MICROCYTIC HYPOCHROMIC

HBA1C - 7.6 %

RETICULOCYTE COUNT - 0.9 %

URINE FOR KETONE BODIES - NEGATIVE


USG REPORT ;

IMPRESSION - NO SONOLOGICAL ABNORMALITY DETECTED 


2D ECHO ;

IMPRESSION - NO RWMA

MODERATE TR + WITH MILD PAH ( ECCENTRIC TYPE

MILD AR + , TRIVIAL MR +

SCLEROTIC AV NO AS MS , IAS INTACT

MAC +

EF 61 %

RV SP2 38 + 10 = 48 MM HG

GOOD LV SYTOLIC FUNCTION

NO DIASTOLIC DYSFUNCTION - NO PE

IVC SIZE - 1.0 CM COLLAPSING


21/4/24 -

HB - 8 GM/DL

TLC-8000 CELLS/CUMM

PLATELETS -3.26LAKHS/CUMM

SMEAR -MICROCYTIC HYPOCHROMIC ANAEMIA

SERUM ELECTROLYTES -

SODIUM - 140 MMOL/L

POTASSIUM- 4.2 MMOL/L

CHLORIDE - 104 MMOL/L

CALCIUM IONISED - 1.16 MMOL/L


22/4/24 -

HB - 7.7 GM/DL

TLC-8500 CELLS/CUMM

PLATELETS -3.4 LAKHS/CUMM

PCV - 24.2 VOL%

MCV- 59.8 FL

MCH - 18.9 PG

RDW-CV - 15.5 %

SMEAR -MICROCYTIC HYPOCHROMIC ANAEMIA

SERUM ELECTROLYTES -

SODIUM - 143 MMOL/L

POTASSIUM- 4.3 MMOL/L

CHLORIDE - 106 MMOL/L

CALCIUM IONISED - 1.15 MMOL/L


URINE CULTURE -NO GROWTH

BLOOD CULTURE -ECOLI ISOLATED

SENSITIVE TO AMOXYCLAV, GENTAMICIN, COTRIMOXAZOLE, AMIKACIN, PIPERACILIN, TAZOBACTAM.


DIAGNOSIS 

SHE THEN CAME TO THIS HOSPITAL ON 18-04-2024 and WAS DIAGNOSED WITH 

1.ENTERIC FEVER

2.DIABETES MELLITUS TYPE II SINCE 9 YEARS WITH UNCONTROLLED SUGARS 

3. IRON 

DEFICIENCY ANEMIA SECONDARY TO NUTRITIONAL CAUSE 

4. DENOVO HYPERTENSION 



Treatment Given

IVF FUSIDEX(0.45% NS+ 5% DEXTROSE)

IVF NS @ 100ML / HR

INJ HAI 40U IN 39ML NS @6ML/HR INCREASE OR DECREASE ACC TO GRBS

INJ MONOCEF 1 GM IV BD X 5DAYS

INJ PAN 40 IV OD

INJ HAI S/C TID ACC TO GRBS

INJ NPH S/C BD ACC TO GRBS

INJ NEOMAL 1 GM IV SOS IF TEMP > 101 F

INJ.IRON SUCROSE 1AMP IN 100ML IN NS IV/OD 2 DOSES

T.PCM 650 MG PO TID 1-1-1

T.OROFER XT PO OD 1-0-0

T.PREGABALIN 75MG PO/SOS 0-0-1

T.CLONAZEPAM MD 0.5MG PO/SOS

 IF ANXIOUS/RESTLESS


DISCHARGE 

THEN, PATIENT WAS ADMITTED, EVALUATED,AND WAS TREATED FOR 6 DAYS.

DATE OF DISCHARGE : 24/04/2024

THEN THE PATIENT WAS DISCHARGED ON 24/04/2024 WITH THE FOLLOWING ADVICE : 

INJ.HUMAN ACTRAPID INSULIN A/C TID 16U-16U-16U

INJ.NPH S/C BD 14U----X----14U

TAB.TELMA 20MG PO OD 1----X----X CONTINUE 

TAB.PAN 40 IV OD FOR 5 DAYS

TAB.OROFER XT PO OD 1----0----0 FOR 30 DAYS

TAB.PREGABALIN 75 MG PO / SOS 0---0---1 FOR 1 WEEK

INJ.IRON SUCROSE 1 AMP IN 100ML IV ALTERNATE DAYS FOR 

PLENTY OF ORAL FLUIDS 

STRICT DIABETIC DIET

IRON RICH DIET


PaJR conversations in sequence 


Narsimha reddy sir : vitals + GRBS [from 18/04/24 to 20/04/24 ( till 8 am )]



Narsimha reddy sir : Yesterday( i.e., 19/05/24)

 8PM - 298 mg/dl - 8U HAI + 8U NPH 

Had 2 Chapathi with Mixed Vegetable Curry 

10PM - 331 mg/dl 


20/05/24

2AM - 228 mg/dl 

20/4/24 :..

8AM -224 mg/dl - 10U HAI + 10U NPH - Had 3 idly with Spice Powder


Rakesh Biswas sir: Please update the fever chart and share the image asap


FEVER CHART [from 18/04/24 to 22/04/24 (till 8 am) ]



GRBS CHART [ from 18/4/24 to 20/04/24 ( till 8 am ) ].....




 


28th OF APRIL, 2024 [ 4th VISIT TO THIS HOSPITAL]

IT WAS REALISED DURING HER 4th VISIT THAT SHE ALSO HAD URINARY TRACT INFECTION (UTI+) and THIS DIAGNOSIS WAS MISSED DURING HER 3RD VISIT and WAS ALSO NOT MENTIONED IN THE 3RD VISIT DISCHARGE SUMMARY, DATED 24-04-2024.

CHIEF COMPLAINTS: FEVER SINCE 2 WEEKS

HISTORY OF PRESENT ILLNESS : PATIENT WAS APPARENTLY ASYMPTOMATIC 2 WEEKS BACK AND THEN SHE DEVELOPED FEVER 2 WEEKS A/W CHILLS AND RIGORS ANS RELIEVED IN BETWEEN BUT SINCE TODAY MORNING THE FEVER IS PRESENT ,HIGH GRADE ,CONTINOUS TYPE A/W CHILLS AND RIGORS ,HEADACHE +,NO AGGRAVATING AND RELIEVING FACTORS 

NO H/O BURNING MICTURATION

NO H/O PAIN ABDOMEN , VOMMITINGS

NO H/O CHEST PAIN , PALPITATIONS

NO H/O COLD , COUGH

NO H/O PEDAL EDEMA,DRUG NON COMPLIANCE

 

HISTORY OF PAST ILLNESS :

K/C/O DM SINCE 9 YEARS AND ON INJ HAI/SC/TID 16U-16U-16U

INJ NPH SC /BD 14U-X-14U

K/C/O HTN SINCE 6 DAYS AND ON TAB TELMA 20MG PO/OD

N/K/C/O THYROID DISORDERS , ASTHMA , TB , EPILEPSY , CAD , CVA


MENSTRUAL HISTORY :

HYSTERECTOMY DONE 9 YEARS AGO


ON EXAMINATION

Pt. Consent was taken.

 Pt.was examined in a well lit room 

PT IS CONSCIOUS, COHERENT,COOPERATIVE

No pallor 

No icterus

No cyanosis 

No clubbing

No lymphadenopathy 

Pitting type of pedal edema is present.(??????)

Family history- Not significant 

Personal history- 

Diet- mixed 

Appetite- normal 

Bowel and bladder movements- normal 

Sleep- inadequate

No addictions 

VITALS:

TEMP-101 F

PULSE RATE 92 BPM

BP 140/90 MMHG

GRBS -256MG/DL

CVS-S1 S2 HEARD NO MURMURS

RS- BAE PRESENT NVB

P/A-SOFT,NON TENDER


Investigations in sequence from November 2023 to  present today

November, 2023

POST LUNCH BLOOD SUGAR 16-11-2023 110 mg/dl

SERUM CREATININE 16-11-2023 0.9

COMPLETE URINE EXAMINATION (CUE) 16-11-2023

COLOUR Pale yellow

APPEARANCE Clear

REACTION Acidic

SP.GRAVITY 1.010

ALBUMIN ++

SUGAR +++

BILE SALTS Nil

BILE PIGMENTS Nil

PUS CELLS 3-6

EPITHELIAL CELLS 2-4

RED BLOOD CELLS Nil

CRYSTALS Nil

CASTS Nil

AMORPHOUS DEPOSITS Absent

OTHERS Nil

ABG 16-11-2023

PH 7.47

PCO2 28.4

PO2 82.9

HCO3 20.5

St.HCO3 22.8

BEB -1.9

BEecf -2.6

TCO2 42.2

O2 Sat 96.9

O2 Count 13.6

COMPLETE URINE EXAMINATION (CUE) 16-11-2023

COLOUR Pale yellow

APPEARANCE Clear

REACTION Acidic

SP.GRAVITY 1.010

ALBUMIN Nil

SUGAR ++++

BILE SALTS Nil

BILE PIGMENTS Nil

PUS CELLS 3-4

EPITHELIAL CELLS 2-4

RED BLOOD CELLS Nil

CRYSTALS Nil

CASTS Nil

AMORPHOUS DEPOSITS Absent

OTHERS Nil

COMPLETE BLOOD PICTURE (CBP) 16-11-2023 10:33:PM

HAEMOGLOBIN 9.0 gm/dl 15.0-12.0 gm/dl

TOTAL COUNT 10800 cells/cumm 10000-4000 cells/cumm

NEUTROPHILS 62 % 80-40 %

LYMPHOCYTES 32 % 40-20 %

EOSINOPHILS 00 % 6-1 %

MONOCYTES 06 % 10-2 %

BASOPHILS 00 % 2-0 %

PLATELET COUNT 3.87

SMEAR microcytic hypochromic anemia

HBsAg-RAPID 16-11-2023 Negative

LIVER FUNCTION TEST (LFT) 16-11-2023

Total Bilurubin 0.51 mg/dl 1-0 mg/dl

Direct Bilurubin 0.20 mg/dl 0.2-0.0 mg/dl

SGOT(AST) 14 IU/L 31-0 IU/L

SGPT(ALT) 19 IU/L 34-0 IU/L

ALKALINE PHOSPHATE 143 IU/L 98-42 IU/L

TOTAL PROTEINS 6.4 gm/dl 8.3-6.4 gm/dl

ALBUMIN 3.91 gm/dl 5.2-3.5 gm/dl

A/G RATIO 1.57

RFT 16-11-2023 10:33:PM

UREA 18 mg/dl

CREATININE 0.7 mg/dl

URIC ACID 5.7 mg/dl

CALCIUM 10.1 mg/dl

PHOSPHOROUS 3.3 mg/dl

SODIUM 135 mEq/L

POTASSIUM 3.7 mEq/L

CHLORIDE 101 mEq/L 98-107 mEq/L

POST LUNCH BLOOD SUGAR 17-11-2023 393 mg/dl

RFT 19-11-2023

UREA 18 mg/dl

CREATININE 0.6 mg/dl

URIC ACID 2.6 mg/dl

CALCIUM 10.1 mg/dl

PHOSPHOROUS 3.4 mg/dl

SODIUM 137 mEq/L

POTASSIUM 4.2 mEq/L

CHLORIDE 102 mEq/L

COMPLETE BLOOD PICTURE (CBP) 20-11-2023

HAEMOGLOBIN 8.9 gm/dl

TOTAL COUNT 12200 cells/cumm

NEUTROPHILS 68 %

LYMPHOCYTES 26 %

EOSINOPHILS 00 %

MONOCYTES 06 %

BASOPHILS 00 % 2-0 %

PLATELET COUNT 4.33

SMEAR Microcytic hypochromic anemia with leukocytosis


From 18-04-24 to 24-04-24

HBsAg-RAPID   18-04-2024    

Negative   


COMPLETE URINE EXAMINATION (CUE)   18-04-2024 

 COLOUR Pale yellow  

 APPEARANCE Clear  

 REACTION Acidic  

 SP.GRAVITY 1.010  

 ALBUMIN Nil  

 SUGAR Nil  

 BILE SALTS Nil  

 BILE PIGMENTS Nil  

 PUS CELLS 3-4  

 EPITHELIAL CELLS 2-3  

 RED BLOOD CELLS Nil  

 CRYSTALS Nil  

 CASTS Nil  

 AMORPHOUS DEPOSITS Absent  

 OTHERS Nil  


 LIVER FUNCTION TEST (LFT)   18-04-2024 

 Total Bilurubin 1.46 mg/dl 1-0 mg/dl

 Direct Bilurubin 0.43 mg/dl 0.2-0.0 mg/dl

 SGOT(AST) 10 IU/L 31-0 IU/L

 SGPT(ALT) 10 IU/L 34-0 IU/L

 ALKALINE PHOSPHATASE 232 IU/L 98-42 IU/L

 TOTAL PROTEINS 7.0 gm/dl 8.3-6.4 gm/dl

 ALBUMIN 3.67 gm/dl 5.2-3.5 gm/dl

 A/G RATIO 1.10

 

 RFT   18-04-2024 12:34:PM


 UREA 37 mg/dl 42-12 mg/dl

 CREATININE 1.3 mg/dl 1.1-0.6 mg/dl

 URIC ACID 4.1 mmol/L 6-2.6 mmol/L

 CALCIUM 9.6 mg/dl 10.2-8.6 mg/dl

 PHOSPHOROUS 3.6 mg/dl 4.5-2.5 mg/dl

 SODIUM 136 mmol/L 145-136 mmol/L

 POTASSIUM 4.6 mmol/L. 5.1-3.5 mmol/L.

 CHLORIDE 98 mmol/L 98-107 mmol/L


POST LUNCH BLOOD SUGAR   18-04-2024 

493 mg/dl 140-0 mg/dl


PERIPHERAL SMEAR   18-04-2024     

RBC : Microcytic hypochromic  

WBC :increased counts on smear   

PLATELET : Adequate   


 ABG   18-04-2024 03:42:PM

 PH 7.41  

 PCO2 24.0  

 PO2 90.8  

 HCO3 15.2  

 St.HCO3 18.0  

 BEB -7.9  

 BEecf -8.4  

 TCO2 32.2  

 O2 Sat 96.6  

 O2 Count 11.8

 

 ABG   18-04-2024 10:54:PM

 PH 7.36  

 PCO2 31.7  

 PO2 39.7  

 HCO3 17.5  

 St.HCO3 18.6  

 BEB -6.8  

 BEecf -6.9  

 TCO2 38.1  

 O2 Sat 75.4  

 O2 Count 7.7  


 SERUM ELECTROLYTES (Na, K, C l)   18-04-2024 10:54:PM

 SODIUM 128 mmol/L 145-136 mmol/L

 POTASSIUM 3.8 mmol/L 5.1-3.5 mmol/L

 CHLORIDE 104 mmol/L 98-107 mmol/L


 SERUM ELECTROLYTES (Na, K, C l)   19-04-2024 11:54:AM

 SODIUM 134 mmol/L 145-136 mmol/L

 POTASSIUM 3.9 mmol/L 5.1-3.5 mmol/L

 CHLORIDE 105 mmol/L 98-107 mmol/L


 COMPLETE URINE EXAMINATION (CUE)   19-04-2024 11:54:AM

 COLOUR Pale yellow  

 APPEARANCE Clear  

 REACTION Acidic  

 SP.GRAVITY 1.010  

 ALBUMIN +  

 SUGAR Nil  

 BILE SALTS Nil  

 BILE PIGMENTS Nil  

 PUS CELLS 2-4  

 EPITHELIAL CELLS 2-3  

 RED BLOOD CELLS Nil  

 CRYSTALS Nil  

 CASTS Nil  

 AMORPHOUS DEPOSITS Absent  

 OTHERS Nil  

ABG   19-04-2024 04:44:PM

 PH 7.42  

 PCO2 28.7  

 PO2 73.8  

 HCO3 18.5  

 St.HCO3 20.5  

 BEB -4.7  

 BEecf -5.1  

 TCO2 39.1  

 O2 Sat 95.7  

 O2 Count 11.4  


 SERUM ELECTROLYTES (Na, K, C l)   19-04-2024 11:06:PM

 SODIUM 137 mmol/L 145-136 mmol/L

 POTASSIUM 4.0 mmol/L 5.1-3.5 mmol/L

 CHLORIDE 105 mmol/L 98-107 mmol/L

 

HEMOGRAM 19/4/24

HB - 7.6

TLC-14,400

PCV - 22.8

RBC - 3.9

SMEAR - MICROCYTIC HYPOCHROMIC

HBA1C - 7.6 %

RETICULOCYTE COUNT - 0.9 %

URINE FOR KETONE BODIES - NEGATIVE

 

USG REPORT ;

IMPRESSION - NO SONOLOGICAL ABNORMALITY DETECTED 

 

2D ECHO ;

IMPRESSION - NO  RWMA

MODERATE TR + WITH MILD PAH ( ECCENTRIC TYPE

MILD AR + , TRIVIAL MR +

SCLEROTIC AV NO AS MS , IAS INTACT

MAC +

EF 61 %

RV SP2 38 + 10 = 48 MM HG

GOOD LV SYTOLIC FUNCTION

NO DIASTOLIC DYSFUNCTION - NO PE

IVC SIZE - 1.0 CM COLLAPSING

 

21/4/24 -

HB - 8 GM/DL

TLC-8000 CELLS/CUMM

PLATELETS -3.2


REFERRAL 

OPHTHALMOLOGY REFERRAL I/V/O DIABETIC RETINOPATHY ON 20/4/24 

IMPRESSION - BE MODERATE NPDR CHANGES NOTED

ADVICE - REVIEW FUNDOSCOPY EVERY 3 MONTHS

 

PSYCHIATRY REFERRAL I/V/O ?MANIA(PSYCHOTIC EPISODE) ON 21/4/24

ADVICE:

T.CLONAZEPAM MD 0.5MG PO/SOS

 IF ANXIOUS/RESTLESS

RELAXATION AND DIVERSION TECHNIQUES EXPLAINED

 

DIETICIAN REFERAL I/V/O UNCONTROLLED SUGARS

ADVICE - DIABETIC DIET EXPLAINED



FROM 28-04-2024 TO 03-05-2024

COMPLETE URINE EXAMINATION (CUE)   28-04-2024 05:16:PM

 COLOUR Pale yellow  

 APPEARANCE Clear  

 REACTION Acidic  

 SP.GRAVITY 1.010  

 ALBUMIN +++  

 SUGAR Nil  

 BILE SALTS Nil  

 BILE PIGMENTS Nil  

 PUS CELLS 4-5  

 EPITHELIAL CELLS 2-4  

 RED BLOOD CELLS Nil  

 CRYSTALS Nil  

 CASTS Nil  

 AMORPHOUS DEPOSITS Absent  

 OTHERS Nil  


 RFT   28-04-2024 05:16:PM

 UREA 21 mg/dl 42-12 mg/dl

 CREATININE 0.9 mg/dl 1.1-0.6 mg/dl

 URIC ACID 2.8 mmol/L 6-2.6 mmol/L

 CALCIUM 10.0 mg/dl 10.2-8.6 mg/dl

 PHOSPHOROUS 2.0 mg/dl 4.5-2.5 mg/dl

 SODIUM 137 mmol/L 145-136 mmol/L

 POTASSIUM 3.6 mmol/L. 5.1-3.5 mmol/L.

 CHLORIDE 103 mmol/L 98-107 mmol/L


POST LUNCH BLOOD SUGAR   28-04-2024 

237 mg/dl 140-0 mg/dl


 WIDAL TEST   28-04-2024 05:19:PM

 S.typhi "O" Antibodies 1:20  

 S.typhi "H" Antibodies 1:40  

 S.PARATYPHI "AH" ANTIBODY No Agglutination seen  

 S.PARATYPHI "BH" ANTIBODY No Agglutination seen  


HEMOGRAM

28/4/24 -

HB-7.7

TLC-16000

PLT-4.07

RBC-4.05

29/4/24

HB-6.3

TLC-13200

PLT-2.77

RBC-3.39

30/4/24

HB-6.1

TLC-97200

PLT-2.99

RBC-3.25


DIAGNOSIS 

ENTERIC FEVER

DIABETES MELLITUS SINCE 9 YEARS

HYPERTENSION SINCE 1 WEEK

WITH ANEMIA-MCHC SECONDARY TO NUTRITIONAL CAUSE

***ALSO URINARY TRACT INFECTION + 

[ IT WAS REALISED DURING HER 4th VISIT (may,2024)  THAT SHE ALSO HAD URINARY TRACT INFECTION (UTI+) and THIS DIAGNOSIS WAS MISSED DURING HER 3rd VISIT and WAS ALSO NOT MENTIONED IN THE 3rd VISIT DISCHARGE SUMMARY, DATED 24-04-2024.]


Treatment Given

INJ AUGMENTIN 1.2GM IV/BD

INJ PAN 40MG IV/OD

INJ HAI S/C TID

INJ NPH S/C BD ACC TO GRBS

T.METFORMIN 500MG PO/OD

TAB TELMA 20MG PO/OD

T.DOLO 650MG PO/SOS

INJ IRON SUCROSE 200MG IN 100ML NS IV/OD


Advice at Discharge [Discharge Date- 3/5/24 ]

T.METFORMIN 500MG PO/OD

TAB TELMA 20MG PO/OD

T.DOLO 650MG PO/SOS


DAILY ACTIVITY CHART













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